SELECTED PUBLICATIONS



Microbial natural products
Secondary metabolites and microbial taxonomy
Pharmacology / Mode of action
Marine natural products

Microbial natural products

RATNAYAKE R., LACEY E., TENNANT S., GILL J.H. & CAPON R.J. 2007. Kibdelones: Novel anticancer polyketides from a rare Australian actinomycete. Chem. Eur. J. 13: 1610 - 1619.

RATNAYAKE R., LACEY E., TENNANT S., GILL, J.H. & CAPON R.J. 2006. Isokibdelones: Novel heterocyclic polyketides from a Kibdelosporangium sp. Org. Lett. 8: 5267- 5270.

CLARK B., CAPON R.J., LACEY E., TENNANT S. & GILL J.H. 2006. Quinolactacins revisited: From lactams to imide and beyond. Org. Biomol. Chem. 4: 1512-1519.

CLARK B., CAPON R.J., LACEY E., TENNANT S. & GILL J.H. 2006. Citrinin revisited: From monomers to dimers and beyond. Org. Biomol. Chem. 4: 1520-1528.

CLARK B., CAPON R.J., LACEY E., TENNANT S. & GILL J.H. 2006. Polyenylpyrroles and polyenylfurans from an Australian isolate of the soil Ascomycete Gymnoascus reessii. Org. Lett. 8: 701-704

STEWART M., CAPON R.J., LACEY E., TENNANT S. & GILL J.H. 2005. Calbistrin E and two other new metabolites from an Australian isolate of Penicillium striatisporum. J. Nat. Prod. 68: 581-584.

CLARK B., CAPON R.J., LACEY E., TENNANT S., GILL J.H., BULHELLER B. & BRINGMANN G. 2005. Gymnoascolides A-C: Aromatic butenolides from an Australian isolate of the soil ascomycete Gymnoascus reessii. J. Nat. Prod. 68: 1226-1230.

CLARK B., CAPON R.J., LACEY E., TENNANT S. & GILL J.H. 2005. Roquefortine E: A New Isoprenylated Diketopiperazine from an Australian Isolate of Gymnoascus reessii. J. Nat. Prod. 2005, 68: 1661-1664.

CAPON R.J., RATNAYAKE R., STEWART M., LACEY E., TENNANT S. & GILL J.H. 2005. Aspergillazines A-E: novel heterocyclic dipeptides from an Australian strain of Aspergillus unilateralis. Org. Biomol. Chem. 3: 123-129.

STEWART M., CAPON R.J., WHITE J.M., LACEY E., TENNANT S., GILL J.H. & SHADDOCK M.P. 2004. Rugulotrosins A and B: Two new antibacterial metabolites from an Australian isolate of a Penicillium sp. J. Nat. Prod. 67: 728-730.

CLARKE B., CAPON, R.J., STEWART M., LACEY E., TENNANT S. & GILL JH. 2004. Blanchaquinone: a new anthraquinone from an Australian Streptomyces sp. J. Nat. Prod. 67: 1729-1731.

CAPON R.J., SKENE C., STEWART M., FORD J., O'HAIR R.A.J., WILLIAMS L., LACEY E., GILL J.H., WICKER J., HEILAND K. & FRIEDEL T. 2003. Aspergillacins A-E: five novel depsipeptides from the marine-derived fungus Aspergillus carneus. Org. Biomol. Chem 1: 1856-1862.

CAPON R.J., SKENE C., LACEY E., GILL J.H., WICKER J., HEILAND K. & FRIEDEL T. 2000. Lorneamides A and B: Two novel aromatic amides from a southern Australian marine actinomycetes. J. Nat. Prod. 63: 1682-1683.

ANDERSON M.G., RICKARDS R.W. & LACEY E. 1999. Structures of Flagranones A, B and C, cyclohexenoxide antibiotics from the nematode-trapping fungus Duddingtonia flagrans. J. Antibiot. 52: 1023-1028.

RICKARDS R.W., ROTHESCHILD J.M. & LACEY E. 1998. Structure of actinotetraose hexatiglate, a unique glucotetraose from an actinomycete bacteria. J. Antibiot. 51: 1093-1098.

O'SHEA M., RICKARDS R.W., ROTHESCHILD J.M. & LACEY E. 1997. Absolute configurations of macrolide antibiotics of the bafilomycin and leucanicidin groups. J. Antibiot. 50: 1073-1077.

LACEY E., GILL J.H., POWER M.L., RICKARDS R.W., O'SHEA M.G. & ROTHSCHILD J.M. 1995. Bafilolides, potent inhibitors of the motility and development of the free-living stages of parasitic nematodes. Int. J. Parasitol. 25: 349-357.

CAPON R.J., STEWARTM., RATNAYAKE R., LACEY E. & GILL J.H. 2007. Citromycetins and Bilains A?C: New Aromatic Polyketides and Diketopiperazines from Australian Marine-Derived and Terrestrial Penicillium spp. J. Nat. Prod. 70, 1746?1752

RATNAYAKE R., FREMLIN L.J., LACEY E., GILL J.H. & CAPON R.J. 2008 Acremolides A-D, Lipodepsipeptides from an Australian Marine Derived Fungus, Acremonium sp. J. Nat. Prod. 71, 403?408


Secondary metabolites and microbial taxonomy

TAN G.Y.A., ROBINSON S., LACEY E. & GOODFELLOW M. 2006. Amycolatopsis australiensis sp. nov., an actinomycete isolated from arid soils. Int. J. Systematic Evol. Microbiol. 56: 2297-2301.

LACEY E. & TENNANT S. 2003. Secondary metabolites - the focus of biodiscovery and perhaps the key to unlocking new depths in taxonomy. Microbiology Australia 24: 34-35.

MURRELL A., DOBSON S.J., YANG X., LACEY E. & BARKER S.C. 2003. A survey of bacterial diversity in ticks, lice and fleas from Australia. Parasitol. Res. 89: 326-334.

BROWN R., LACEY E., ROBINSON S., GILL J.H., MALDONADO L.A. & GOODFELLOW M. Characterisation of staurosporine-producing Streptomycetes. 12th International Symposium on the Biology of Actinomycetes. Vancouver, British Columbia, Canada; 2001: p92.

RASHIDIAN E., SEMBIRING L., LACEY E., GOODFELLOW M. & WARD A.C. Mapping metabolites to Streptomycete taxonomy. 12th International Symposium on the Biology of Actinomycetes. Vancouver, British Columbia, Canada; 2001: p100.



Pharmacology / Mode of action

GILL J.H. & LACEY E. 1998. Avermectin/milbemycin resistance in trichostrongylid nematodes. Int. J. Parasitol. 28: 863-877.

GILL J.H. & LACEY E. 1993. In vitro activity of paraherquamide against the free living stages of Haemonchus contortus, Trichostrongylus colubriformis and Ostertagia circumcincta. Int. J. Parasitol. 23: 375 381.

LACEY E. 1988. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. Int. J. Parasitol. 18: 885 936.



Marine natural products

CAPON R.J., VUONG D., LACEY E. & GILL J.H. 2005. (-) Echinobetaine A: isolation, structure elucidation, synthesis and preliminary SAR studies on a new nematocidal betaine from a southern Australian marine sponge, Echinodictyum sp. J. Nat. Prod. 68: 179-182.

CAPON R.J., VUONG D., McNALLY M., PETERLE T., TROTTER N., LACEY E. & GILL J.H. 2005. (+) Echinobetaine B: Isolation, structure elucidation, synthesis and preliminary SAR studies on a new nematocidal betaine from a southern Australian marine sponge, Echinodictyum sp. Org. Biomol. Chem. 3: 118-122.

CAPON R.J., SKENE C., LIU E.H., LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2004. Esmodil: an acetylcholine mimetic resurfaces in a Southern Australian marine sponge Raspailia (Raspailia) sp. Nat. Prod. Res. 18: 305-309.

CAPON R.J. SKENE C., LIU EH., LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2004. Nematocidal thiocyanatins from a southern Australian marine sponge Oceanapia sp. J. Nat. Prod. 67: 1277-1282.

NARKOWICZ C.K., BLACKMAN A.J., LACEY E., GILL J.H. & HEILAND K. 2002. Convolutindole A and Convolulamine H, new nematocidal brominated alkaloids from the marine bryozoan Amathia convoluta. J. Nat. Prod. 65: 938-941.

CAPON R.J., SKENE C., VUONG D., LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2002. Equilibrating isomers: bromoindoles and a seco-xanthine encountered during a study of nematocides from the southern Australian marine sponge Hymeniacidon sp. J. Nat. Prod. 65: 368-370.

CAPON R.J., FORD J., LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2002. Phoriospongins A and B: Two new nematocidal depsipeptides from the Australian marine sponges Callyspongia bilamellata and Phoriospongia sp. J. Nat. Prod. 65: 358-363.

VOUNG D., CAPON R.J., LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2001. Onnamide F: A new nematocide from a southern Australian marine sponge, Trachycladus laevispirulifer. J. Nat. Prod. 64: 640-642.

CAPON R.J., SKENE C., LIU E.T.-H, LACEY E., GILL J.H., HEILAND K. & FRIEDEL T. 2001. The isolation and synthesis of novel nematocides dithiocyanates from an Australian marine sponge, Oceanopia sp. J. Org. Chem. 66: 7765-7769.

CAPON R.J., SKENE C., LACEY E., GILL J.H., WADSWORTH D. & FRIEDEL T. 1999. Geodin A magnesium salt: a novel nematocide from a southern Australian marine sponge, Geodia. J. Nat. Prod. 62: 1256-1259.

OVENDEN S.P.B., CAPON R.J., LACEY E., GILL J.H., FRIEDEL T. & WADSWORTH D. 1999. Amphilactams A-D: Novel nematocides from southern Australian marine sponges of the genus Amphimedon. J. Org. Chem. 64: 1140-1144.

CAPON R.J., BARROW R.A., ROCHFORT S. JOBLING M., SKENE C., LACEY E., GILL J.H., FRIEDEL T. & WADSWORTH D. 1998. Marine nematocides: Tetrahydrofurans from a southern Australian brown alga, Notheia anomala. Tetrahedron 54: 2227-2242.

Home | Business Development | Micorbial Diversity | Metabolic diversity | Chemical Diversity | Bioassay Platforms

Dereplication | Fermentation | Publications | Bioaustralis | Contact Us | ©2003 MICROBIAL SCREENING TECHNOLOGIES